Myrcene is one of the most common types of terpenes in the cannabis plant producing, as studies have shown, approximately 50% of the terpene in the plant. Studies have also shown that while it makes up a considerable amount of the plant, it is actually a forerunner to many other terpenes in the cannabis plant which means it is able to help them develop.
Cannabinoid Receptor 1
A cannabinoid receptor antagonist, also known simply as a cannabinoid antagonist or as an anticannabinoid, is a type of cannabinoidergic drug that binds to cannabinoid receptors (CBR) and prevents their activation by endocannabinoids. They include antagonists, inverse agonists, and antibodies of CBRs. The discovery of the endocannabinoid system led to the development of CB1 receptor antagonists.
Cannabinoid Receptor 2
Cannabinoid receptors are of a class of cell membrane receptors under the G protein-coupled receptor superfamily. Cannabinoid receptors are activated by three major groups of ligands: endocannabinoids, produced by the mammillary body; plant cannabinoids (such as Cannabidiol, produced by the cannabis plant); and synthetic cannabinoids (such as HU-210). All of the endocannabinoids and plant cannabinoids are lipophilic, such as fat soluble compounds.
Myrcene, specifically β-myrcene, is a monoterpene and the most common terpene produced by cannabis (some varieties contain up to 60% of the essential oil). Its aroma has been described as musky, earthy, herbal – akin to cloves. A high myrcene level in cannabis (usually above 0.5%) results in the well-known “couch-lock” effect of classic Indica strains. Myrcene is found in oil of hops, citrus fruits, bay leaves, eucalyptus, wild thyme, lemon grass and many other plants.
Myrcene has some very special medicinal properties, including lowering the resistance across the blood to brain barrier, allowing itself and many other chemicals to cross the barrier easier and more quickly. In the case of cannabinoids (like THC), myrcene allows the effects of the cannabinoid to take effect more quickly. More uniquely still, myrcene has been shown to increase the maximum saturation level of the CB1 receptor, allowing for a greater maximum psychoactive effect.
Myrcene is a potent analgesic, anti-inflammatory, antibiotic and antimutagenic. It blocks the action of cytochrome, aflatoxin B and other pro-mutagenic carcinogens. The Bonamin et al study focused on the role of β-myrcene in preventing peptic ulcer disease. The study revealed that β-myrcene acts as an inhibitor of gastric and duodenal ulcers, suggesting it may be helpful in preventing peptic ulcer disease. Its sedative and relaxing effects also make it ideal for the treatment of insomnia and pain.
Since myrcene is normally found in essential oil from citrus fruit, many claim eating a fresh mango about 45 minutes before consuming cannabis will result in a faster onset of psycho activity and greater intensity. Be sure to choose a mango that is ripe otherwise the myrcene level will be too low to make a difference.
All You Need To Know About Myrcene
When one considers the plant marijuana the majority of people will imagine individuals in the hippie ear smoking “green leaves” to experience sense of euphoria. Nowadays, people continue to enjoy this sensation but marijuana is also used in medical research to manage conditions such as cancer and epilepsy. What many individuals do not realize is that the compounds that provide the different sensations are, in fact, different in the marijuana themselves with the terpenes being used primarily for therapy. The terpenes are the items contributing to the pungent odor, but they can be beneficial and this article will provide information on the canniboid terpenes known as myrcene.
Myrcene is one of the most common types of terpenes in the cannabis plant producing, as studies have shown, approximately 50% of the terpene in the plant. Studies have also shown that while it makes up a considerable amount of the plant, it is actually a forerunner to many other terpenes in the cannabis plant which means it is able to help them develop. This makes it beneficial as a means of promoting therapeutic compounds. Of course, myrcene is found not only in cannabis and can be obtained via other plants if necessary including basil and mangoes.
As is mentioned, the myrcene is able to provide a highly beneficial therapeutic effect that is used in medicinal marijuana. It is most commonly utilized as a product for relaxing muscles and pain relief; however, it can also be utilized as an anti-inflammatory for specific conditions. Unlike other terpenes, myrcene is able to affect the permeability of cell membranes meaning it is able to regulate terpenes in the body either enhancing or buffering the overall sensations. Due to the compound (myrcene) possessing the ability to control cell membranes, it is possible for the myrcene to determine the potency of the terpenes. This is a strong example of the entourage effect where both terpenes and cannabis compounds operate together to enhance the therapeutic effects from a single terpene intake.
In addition to providing physical medical relief, the myrcene is also able to contribute to mental health relief including acting as an anti-depressant or anti-anxiety medication. Studies have shown that the calming effect can improve the mood of the user and promote better well-being. Studies have also shown that the use of this terpene is beneficial for those individuals suffering from psychosis and can reduce the need for traditional pharmaceutical usage.